BTTAA是一种 Cu(I) 稳定配体。能够长时间保持Cu(I)的催化能力，从而更好的进行ADC合成。BTTAA 的性能远远优于 THPTA 或 TBTA。

结构图：

中文简介：

BTTAA 是最新一代的 CuAAC 水溶性加速配体，与上一代配体（例如 THPTA 或 TBTA）相比，它提供了更大的速率增强。更重要的是，它最大限度地减少了对所探测细胞或生物体生理状态的扰动，并通过进一步降低催化剂制剂中的铜负载，实现与抑制细胞细胞毒性的有效生物偶联。

英文简介：

BTTAA is a newest generation, water-soluble accelerating ligand for CuAAC that provides much greater rate enhancement compared to previous generation ligands (e.g. THPTA or TBTA). More importantly, it minimizes perturbations to the physiological state of the cells or organisms probed and allows for effective bioconjugation with suppressed cell cytotoxicity by further lowering copper loading in the catalyst formulation.

ClickChemistryTools点击化学铜稳定配体BTTAA选购指南--文献参考：

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