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目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5324Alexa Fluor? 488 Rat Anti-mouse CD206 (MMR) Antibody (S-R498)

Alexa Fluor? 488 Rat Anti-mouse CD206 (MMR) Antibody (S-R498)
  • Alexa Fluor? 488 Rat Anti-mouse CD206 (MMR) Antibody (S-R498)
參考價(jià) 1102
具體成交價(jià)以合同協(xié)議為準(zhǔn)
參考價(jià) 1102
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 Starter/斯達(dá)特
  • 型號(hào) S0B5324
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 杭州市
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更新時(shí)間:2025-07-12 20:28:36瀏覽次數(shù):53評(píng)價(jià)

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Alexa Fluor? 488 Rat Anti-mouse CD206 (MMR) Antibody (S-R498)

CD206, also known as the mannose receptor (MR) or mannose receptor C type 1 (MRC1), is a transmembrane glycoprotein that belongs to the C-type lectin family. It is predominantly expressed by tissue macrophages, dendritic cells, and certain lymphatic or liver endothelial cells. CD206 recognizes and mediates endocytosis of pathogens by binding to glycoproteins terminated with mannose. This receptor serves as a homeostatic receptor by binding and scavenging unwanted high mannose N-linked glycoproteins as well as pituitary hormones from the circulation. In addition, CD206 is a marker for the M2 phenotype of macrophages, which are involved in immunosuppression, tissue remodeling, and Th2 effector responses. Its expression is regulated by various cytokines and is considered a marker of an M2-like macrophage phenotype.

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