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目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5156Rat Anti-Mouse/Human CD49f Antibody (S-R707)

Rat Anti-Mouse/Human CD49f Antibody (S-R707)
  • Rat Anti-Mouse/Human CD49f Antibody (S-R707)
參考價 600
具體成交價以合同協(xié)議為準
參考價 600
具體成交價以合同協(xié)議為準
  • 品牌 Starter/斯達特
  • 型號 S0B5156
  • 廠商性質 生產(chǎn)商
  • 所在地 杭州市
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更新時間:2025-07-12 14:53:16瀏覽次數(shù):37評價

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Rat Anti-Mouse/Human CD49f Antibody (S-R707)

CD49f, also known as integrin α6 subunit, is a type I transmembrane glycoprotein encoded by the ITGA6 gene. It belongs to the α-subfamily of integrins and can form heterodimers with β1 (CD29) or β4 (CD104) subunits to create functional receptors such as α6β1 or α6β4. These receptors play crucial roles in cell adhesion, migration, and signaling. CD49f is highly expressed in various cell types, including T cells, monocytes, platelets, epithelial cells, and certain stem cells. In cancer biology, CD49f has been identified as a marker for tumor-initiating cells (TICs) in hepatocellular carcinoma (HCC), where it is associated with cell stemness, immune evasion, and the formation of an immunosuppressive tumor microenvironment. Additionally, CD49f has been used as a marker for human astrocytes and has shown potential in studying neurodegenerative diseases.

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