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目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5157Rat Anti-Mouse MERTK Antibody (S-R603)

Rat Anti-Mouse MERTK Antibody (S-R603)
  • Rat Anti-Mouse MERTK Antibody (S-R603)
參考價 600
具體成交價以合同協(xié)議為準(zhǔn)
參考價 600
具體成交價以合同協(xié)議為準(zhǔn)
  • 品牌 Starter/斯達(dá)特
  • 型號 S0B5157
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 杭州市
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更新時間:2025-07-12 14:51:18瀏覽次數(shù):31評價

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Rat Anti-Mouse MERTK Antibody (S-R603)

MERTK, also known as MER proto-oncogene tyrosine kinase, is a receptor tyrosine kinase and a member of the TAM (TYRO3, AXL, MERTK) family. It plays crucial roles in various physiological processes, including cell survival, migration, differentiation, and the phagocytosis of apoptotic cells, a process known as efferocytosis. MERTK is expressed in multiple tissues, such as macrophages and retinal pigment epithelial cells, and is involved in regulating immune responses and maintaining tissue homeostasis. In the immune system, MERTK helps macrophages clear apoptotic cells and inhibits the innate immune response by activating STAT1, which induces the production of suppressors of cytokine signaling (SOCS1 and SOCS3). Abnormal expression of MERTK has been linked to several diseases, including retinitis pigmentosa and certain cancers, making it a potential therapeutic target in cancer treatment.

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