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目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5070Mouse Anti-Human CD61 Antibody (S-R618)

Mouse Anti-Human CD61 Antibody (S-R618)
  • Mouse Anti-Human CD61 Antibody (S-R618)
參考價 600
具體成交價以合同協議為準
參考價 600
具體成交價以合同協議為準
  • 品牌 Starter/斯達特
  • 型號 S0B5070
  • 廠商性質 生產商
  • 所在地 杭州市
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更新時間:2025-07-12 12:36:15瀏覽次數:26評價

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Mouse Anti-Human CD61 Antibody (S-R618)

CD61, also known as integrin β3 or GPIIIa, is a membrane glycoprotein that forms heterodimeric complexes with other integrins, such as CD41 (forming the GPIIb/IIIa complex) and CD51 (forming the αvβ3 integrin). It is primarily expressed on platelets, megakaryocytes, endothelial cells, osteoclasts, and some tumor cells. The CD61/CD41 complex is crucial for platelet aggregation and blood clotting through interactions with fibrinogen and von Willebrand factor. Additionally, CD61 plays a role in cell adhesion, migration, and invasion in various physiological and pathological processes, including tumor metastasis and viral infections. In clinical settings, CD61 is used as a biomarker for identifying platelets and megakaryocytes, and its upregulation in tumors is associated with poor prognosis in several cancers.

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