保存条件：-80°C(dryice)保质期：3-18month英文名：TMPRSS2Lentivirus数量：1供应商：BPSBioscienceInc
- 保存条件：
-80°C (dry ice)
- 保质期：
3-18 month
- 英文名：
TMPRSS2 Lentivirus
- 数量：
1
- 供应商：
BPS Bioscience Inc.
- CAS号：
/
- 规格：
100 µl
Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID19. TMPRSS2 primes the spike protein by cleaving at the S1/S2 site, leading to the virus fusing to the respiratory epithelia on the cell surface through binding to ACE2. Blocking TMPRSS2 activity could potentially be an effective clinical therapy for .
The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter.
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