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提供商：BPSBioscience服務(wù)名稱(chēng)：BPSBioscience的激酶篩選和檢測(cè)服務(wù)AccelerateyourdrugdiscoveryprogramwithKinaseScreeningandProfilingServicesfromBPSBioscience,Inc

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提供商：
BPS Bioscience
服務(wù)名稱(chēng)：
BPS Bioscience的激酶篩選和檢測(cè)服務(wù)

Accelerate your drug discovery program with Kinase Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:

- Screen for inhibitors/targets using our unique panel of 75+ assays
- Select from IC50 determination and single point concentrations
- Receive data within days of compound submission
- Perform follow-up studies using the same proteins manufactured in-house
- Get questions answered or project guidance in a time-efficient manner

Biochemical Assays

Lipid:

PI3Kα (p110α/p85α)	PI3Kβ (p110β/p85α)	PI3Kδ (p110δ/p85α)	PI3Kγ (p110γ/PIK3R5)
SPHK1

Tyrosine:

Abl	c-Src	FGFR3(V443M)	PDGFRα
Abl-1 (T315I)	EGFR (WT)	FGFR4	PDGFRα(D842Y)
ALK	EGFR (L858R)	Flt1	RET
ALK2	EGFR (T790M)	Flt3	ROS1
AXL	EGFR (L858R, T790M)	FYN	SYK
BTK	EGFR(T790M, C797S,L858R)	HER2	TYK2
cKIT(D816V)	EGFR (murine)	HER4	TYRO3
cKIT(V654A)	EphA2	Jak1	VEGFR2/KDR
cMet	EphB4	Jak2(JH2)	Yes1
cMet (exon 14 Del)	FAK	Jak2(JH2)(V617F)
cMet (WT)	FGFR2	Jak3
cMer	FGFR3(L496V)	FGFR2
CSF1R(FMS)	FGFR3(V443L)	Lck

Serine-Threonine:

AKT	CDK4/CyclinD1	GSK3a	PIM2
Aurora A	CDK4/CyclinD3	GSK3b	PIM3
BRAF	CDK5/p25	HPK1/MAP4K1	RIPK1
BRAF (V600E)	CDK6/CyclinD3	IKKβ	RIPK2
Casein Kinase 1	CDK7/CyclinH1/ MNET1	MNK1	TAK1-TAB1
CDK1/CyclinB1	CDK9/CyclinT1	p38	TBK1
CDK2/CyclinA2	CDK12/CyclinK	PLK1	TNIK
CDK2/CyclinE1	cRAF	PIM1	TTK(Msp1)

Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.

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