Bag-1 Polyclonal Antibody

抗体，也叫免疫球蛋白（Ig），是一种能特异性结合抗原的糖蛋白，而抗原是在易感染动物体内引发抗体产生的物质。在体内，抗体是由于外源性分子的侵袭而产生的?？固逡砸桓龌蛘叨喔鯵字形单体存在，每个Y字形单体由4条多肽链组成，包含两条相同的重链和两条相同的轻链。轻链和重链是根据它们的分子量大小来命名的。Y字形结构的顶端是可变区，为抗原结合部位。任何一个抗体的轻链都可以分为κ或λ型（基于小分子多肽结构上的差异），每一个抗体的重链则决定了它的类或型。

产品详情

Bag-1 Polyclonal Antibody detects endogenous levels of Bag-1 protein.

免疫原详细信息

The antiserum was produced against synthesized peptide derived from the Internal region of human BAG1. AA range:41-90

相关试剂

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

背景

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

备注：图片仅供参考。仅供科研，不可用于临床。