目錄:漠寶（廈門）生物科技有限公司>>重組蛋白>> Z03275M-CSF, Mouse
| 參考價(jià) | ￥600-￥2200 |
參考價(jià)：￥600 ~ ￥2200
10 μg 50 μg
供貨周期:一周 規(guī)格:10 μg, 50 μg 貨號(hào):Z03275 應(yīng)用領(lǐng)域:醫(yī)療衛(wèi)生,環(huán)保,食品/農(nóng)產(chǎn)品,生物產(chǎn)業(yè),制藥/生物制藥 主要用途:是一種造血生長因子
>| 10 μg | 600元 | 1件可售 |
| 50 μg | 2200元 | 1件可售 |
更新時(shí)間：2025-07-16 15:51:40瀏覽次數(shù)：73評(píng)價(jià)
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| 供貨周期 | 一周 | 規(guī)格 | 10 μg, 50 μg |
|---|---|---|---|
| 貨號(hào) | Z03275 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,食品/農(nóng)產(chǎn)品,生物產(chǎn)業(yè),制藥/生物制藥 |
| 主要用途 | 是一種造血生長因子 |
Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. In mammals, it exits three isoforms, which invariably share an N-terminal 32-aa signal peptide, a 149-residue growth factor domain, a 21-residue transmembrane region and a 37-aa cytoplasmictail. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers. The biological activity of human M-CSF is maintained within the 149-aa growth factor domain, and it is only active in the disulfide-linked dimeric form, which is bonded at Cys63.
產(chǎn)品簡介
Species： Mouse
Protein Construction ：Expressed with an N-terminal Met. M-CSF (Lys33-Pro187) Accession # P07141
Purity ：> 95% as analyzed by SDS-PAGE
Endotoxin Level ：< 0.2 EU/μg of protein by gel clotting method
Biological Activity： ED50 < 3.0 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 3.3 × 105 units/mg.
Expression System： E. coli
Apparent Molecular Weight ：~30 kDa, on SDS-PAGE under non-reducing conditions.
Formulation： Lyophilized after extensive dialysis against 50 mM Tris, 150 mM NaCl, pH 8.0.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O up to 100 μg/ml. Storage & Stability： Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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