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CAD (phospho Thr456) rabbit pAb
  • CAD (phospho Thr456) rabbit pAb

更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsIHC,ELISAReactivityHuman,MouseDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-CAD (T456) Polyclonal Antibody detects endogenous levels of CAD protein only when phosphorylated at T456.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471

  • Uniprot No

    P27708

  • Alternative names

    CAD; CAD protein

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase(CAD) Homo sapiens The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

  • Other

    CAD, CAD protein

  • Mol.Wt (Da)

    242984

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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