详细介绍
PCNA 增殖细胞核抗原?
广州健仑生物科技有限公司
PCNA 是和细胞周期相关的36kD的核蛋白,是细胞DNA合成所必需的蛋白。此抗体可作为细胞增殖指数的主要参考依据,用于研究恶性肿瘤的细胞增殖和判断其恶性度,对肿瘤的治疗及预后的研究有一定的意义。
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PCNA 增殖细胞核抗原??
【产品介绍】
细胞定位:细胞核
克隆号:PC10
适用组织:石蜡/冰冻
阳性对照:扁桃体
抗原修复:热修复(柠檬酸)
抗体孵育时间:30-60min
产品编号 | 抗体名称 | 克隆型别 |
OB181 | NeuN(神经元特异核蛋白) | A60 |
OB182 | NF(神经丝蛋白) | 2F11 |
OB183 | NGFR试剂 | MRQ-21 |
OB184 | nm23(肿瘤转移抑制基因蛋白) | 37.6 |
OB185 | NSE(神经元特异性烯醇化酶) | E27 |
OB186 | OCT-2(胚胎干细胞关键蛋白2) | MRQ-2 |
OB187 | OCT-4(胚胎干细胞关键蛋白4) | MRQ-10 |
OB188 | Olig2(少突胶质细胞转录因子2) | 211F1.1 |
OB189 | p120 Catenin(p120连接素) | MRQ-5 |
OB190 | P16(p16蛋白) | AbM51100-10 |
OB191 | P27kip1(细胞周期调节和肿瘤抑制因子) | SX53G8 |
OB192 | P40 (p40蛋白) | ZR8 |
OB193 | P504s( α-甲基酰基辅酶A消旋酶) | 13H4 |
OB194 | P53(p53蛋白) | DO7 |
OB195 | P57Kip2(有丝分裂抑制因子) | Kp10 |
OB196 | P63(p63蛋白) | 2B10 |
OB197 | P63(p63蛋白) | 4A4 |
OB198 | PAX-5(B细胞系特异性激活蛋白) | SP34 |
OB199 | PAX-8(转录因子8) | MRQ-50 |
OB200 | PCNA() | PC10 |
PCNA
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【公司名称】 广州健仑生物科技有限公司
【市场部】 欧
【】
【腾讯 】
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室
有上皮肿瘤细胞核SIP1染色阳性的肿瘤更晚期。有更多的淋巴结转移。内皮细胞中表达SNAI1预示患者存活率降低,肿瘤大小增加。而基质细胞TWIST表达与高复发风险有。
病人和医生往往不知道手术切除癌变组织后是否很成功,直到手术几个月后再进行扫描时才能知道。现在,一种新的纳米颗??梢愿绲叵允净颊咴谑质鹾笫欠癯晒η谐巳堪┍渥橹?。
这种纳米颗粒被称为纳米耀斑(nanoflares)。在实验时,颗?;嵋栏接谘貉分械拿恳桓龅ザ赖陌┫赴?,然后会发光。通过激光的辅助可以检测到癌细胞或对其分类。因为有很多不同类型的癌细胞,其中有一些癌细胞远远比其他的更加致命,通过使用这个技术可以检测到这些更致命癌细胞并采集它们,因为这些细胞在采集之后还可以在培养皿中进行培养,用纳米颗?;箍梢栽诟∪苏嬲瘟魄?,更容易地测试一些潜在的治疗方案。
研究人员表明,目前该纳米颗粒可检测小鼠不同类型的抗原抗体癌细胞。他们还表明,纳米颗粒在添加进人类血液后也能识别出抗原抗体癌细胞。他们下一步是确定该颗粒能否从患者体内提取的血液样本中发现癌细胞。
SIP1-positive tumors with epithelial tumor nuclei are more advanced. There are more lymph node metastases. The expression of SNAI1 in endothelial cells predicts a decrease in patient survival and an increase in tumor size. The expression of stromal cells TWIST is associated with a high risk of recurrence.
Patients and doctors often do not know whether successful surgical resection of cancerous tissue is successful until a few months after the surgery before scanning. Now, a new nanoparticle can show earlier whether the patient successfully resected all cancerous tissue after surgery.
This type of nanoparticle is called nanoflares. During the experiment, the particles attach to each individual cancer cell in the blood sample and then glow. Cancer cells can be detected or classified by the help of laser. Because there are many different types of cancer cells, some of which are far more lethal than others, these more deadly cancer cells can be detected and harvested using this technique because they can also be collected in a Petri dish For incubation, using nanoparticles also makes it easier to test some potential treatment options before actually treating the patient.
Researchers have shown that at present the nanoparticles can detect different types of antigen in mice antibody cancer cells. They also show that nanoparticles can also recognize antigen-presenting cancer cells when added to human blood. Their next step is to determine if the particle can find cancer cells in blood samples taken from the patient's body.