目錄:北京索萊寶科技有限公司>>抗體>>一抗>> K200018MAnti-BCL2 Monoclonal一抗
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 100ul |
|---|---|---|---|
| 貨號 | K200018M | 應用領域 | 醫(yī)療衛(wèi)生,化工,生物產業(yè),石油 |
| 主要用途 | BCL2 is an integral outer mitochondrial |
Anti-BCL2 Monoclonal一抗
宿主 Mouse
英文名稱 Anti-BCL2 Monoclonal Antibody
別名 Bcl-2;PPP1R50;Apoptosis regulator Bcl 2;B cell leukemia/lymphoma 2
應用 WB IF
稀釋比例 WB 1:1000-2000. IF 1:100-200.
交叉反應 Human Mouse Rat
蛋白分子量 26kDa
Gene ID 596
保存 Store at -20°C. Avoid freeze / thaw cycles.
儲存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法 Affinity purification
亞型 IgG1
免疫原 A synthetic peptide coupled to KLH
性狀 液體
Public Immunogen Range A synthetic peptide coupled to KLH
Swiss Prot P10415
Subcellular Locations Endoplasmic reticulum membrane Mitochondrion outer membrane Nucleus membrane Single-pass membrane protein
克隆號 6B5
克隆類型 Monoclonal Antibody
背景資料 BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
參考文獻：
《Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo》 作者:Yuan Ma,Wenting Zhao,Yiding Li,Yufei Pan,Shuhe Wang,Yuejie Zhu,Lingxuan Kong,Zhu Guan,Jiancheng Wang,Lihe Zhang,Zhenjun Yang 期刊:Biomaterials 影響因子:10.273 PMID:30660994
Anti-BCL2 Monoclonal一抗
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