CBP10587 | |
Format | Genomic DNA |
Description | IDH1 R132S lies within the active site of the Idh1 protein. R132S confers a gain of function to Idh1, as indicated by increased conversion of alpha-ketoglutarate to the onco-metabolite 2HG (R(-)-2-hydroxyglutarate) in cell culture. |
Technical Data | |
DNA Change | N/A |
AA Change | p.R132S |
Mutation type | Substitution - Missense |
Zygosity | N/A |
Allelic Frequency | N/A |
Transcript | N/A |
Cosmic ID | N/A |
Chr position(GRCh37) | N/A |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |