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CBP10182 | |
| Format | Genomic DNA |
| Description | TP53 R213Q lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). R213Q results in a mild increase in cell proliferation in culture and increased tumor growth in animal models (PMID: 8080050), and therefore is predicted to confer a loss of function to the Tp53 protein. |
| Technical Data | |
| DNA Change | c.638G>A |
| AA Change | p.R213Q |
| Mutation type | Substitution - Nonsense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10735 |
| Chr position(GRCh37) | chr17:7578211 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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