| CBP10541 | |
| Format | Genomic DNA |
| Description | CDK12, cyclin dependent kinase 12, is a key regulator of transcription elongation, regulates the expression of genes involved in DNA repair, and is required for the maintenance of genomic stability (PMID: 24554720; PMID: 22012619). Loss and/or inactivation of CDK12 has been commonly observed in many solid tumor types, including prostate (PMID: 29906450, PMID: 31640893), breast, ovarian, endometrial, uterine (PMID: 30104286), and is a likely tumor suppressor (PMID: 30319007). |
| Technical Data | |
| DNA Change: | c.3262C>T |
| AA Change | p.Q1088* |
| Mutation type | Nonsense_Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 33.33% |
| Transcript | NM_016507.4 |
| Cosmic ID | COSM472690 |
| Chr position(GRCh37) | chr17:37681093 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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