CBP73267 | |
| I. Introduction | |
Cell Line Name： | FGFR2-AHCYL1/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: | Negative |
| II.Background | |
FGFR2-AHCYL1 results from the fusion of FGFR2 and AHCYL1, resulting in the ability to activate MAPK signaling and induce transformation of cells in culture and in animal models (PMID: 24122810). FGFR2-AHCYL1 has been identified in intrahepatic cholangiocarcinoma (PMID: 24122810). | |
| III. Representative Data | |
1. WB of FGFR2-AHCYL1/BaF3
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2. Sanger of FGFR2-AHCYL1/BaF3
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3. Anti-proliferation assay | |
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Figure 3. CTG Proliferation Assay of BaF3 FGFR2-AHCYL1 Cells(C1) | |
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