1-Azakenpaullone 676596-65-9

1-Azakenpaullone
分子式：C15 H10 Br N3 O   分子量：328.16
 
產(chǎn)品描述
1-Azakenpaullone是一種細(xì)胞滲透性的、有效的、ATP競(jìng)爭(zhēng)性的GSK-3β抑制劑，IC50為18nM
靶點(diǎn)
GSK-3β
 
       
IC50
18 nM
 
       
生物活性
A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM), and displays ~100-200 fold greater selectivity over Cdk1/B and Cdk5/p25 (IC50 = 2 µM and 4.2 µM, respectively). Also available as a 10 mM solution in DMSO
溶解性
DMSO (~ 100 mg/ml)
穩(wěn)定性
2年 -20°C粉狀，6月-80°C溶于DMSO