亚洲精品综合日韩中文字幕网站_精品综合久久久久97_中文在线天堂网www_久久精品免费一区二区三区_91久久国产综合精品女同国语_久久资源总站在线国产成人

Desmin is a protein that in humans is encoded by the DES gene. Desmin is a subunit of intermediate filaments in cardiac muscle, skeletal muscle and smooth muscle tissue. In cardiac muscle, desmin is present in Z-discs and intercalated discs and regulates sarcomere architecture. Desmin-related myofibrillar myopathy （DRM or desminopathy） is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin which by changing the protein structure prevents it from forming protein filaments, and rather, forms aggregates of desmin and other proteins throughout the cell. Desmin has been evaluated for role in assessing the depth of invasion of urothelial carcinoma in TURBT specimens.